Search on: ANTINEOPLASTIC AGENTS, HORMONAL 
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Descriptor English:   Antineoplastic Agents, Hormonal 
Descriptor Spanish:   Antineoplásicos Hormonales 
Descriptor Portuguese:   Antineoplásicos Hormonais 
Synonyms English:   Hormonal Antineoplastic Agents  
Tree Number:   D27.505.954.248.169
Definition English:   Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079) 
Indexing Annotation English:   consider also NEOPLASMS, HORMONE-DEPENDENT /drug ther
History Note English:   96 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   32835 
Unique Identifier:   D018931 

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